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This compensatory response is called reflex tachycardia

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The study found that treatment with Tesofensine led to greater weight reduction compared to placebo, with mean weight loss percentages of 4.5%, 9.2%, and 10.6% higher for the 0.25 mg, 0.5 mg, and 1.0 mg doses, respectively

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Taken together, these findings suggest that NSBSO-induced GSH depletion and synthesis inhibition can elevate intracellular ROS, thereby activating the caspase family, leading to GSDME cleavage and cell pyroptosis

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